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Research Articles
Chemical composition and testosterone level enhancing property of Sterculia oblonga leaf essential oil in male albino rats
1 PhD, Professor of Natural Product Chemistry, Department of Chemistry, University of Calabar, Calabar, Cross River State, Nigeria
2 MSc, Lecturer in Organic Chemistry, Department of Chemistry, University of Calabar, Calabar, Cross River State, Nigeria
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Frank N I Morah
Chemistry Department, University of Calabar, Calabar, Cross River State,
Nigeria
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Article ID: 100024P16FM2019
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Morah FNI, Bisong EA. Chemical composition and testosterone level enhancing property of Sterculia oblonga leaf essential oil in male albino rats. Edorium J Public Health 2019;6:100024P16FM2019.ABSTRACT
Aim: Sterculia oblonga is an African medicinal plant used to enhance male fertility. The aim of the present study is to determine the chemical composition and testosterone level enhancingproperty of its leaf essential oil in male albino rats.
Methods: Fresh leaves of S. oblonga were ground and steam-distilled to get its essential oil. The individual constituents of the essential oil were separated by gas chromatography and identified by mass spectrometry. The rats were fed with different doses of the essential oil for one week. The level of testosterone in their blood serum after one week was determined using ultraviolet (UV)-spectrophotometer at wave length of 450 nm.
Results: The essential oil contains 33 constituents and it increased testosterone level in the blood serum of the albino rats.
Conclusion: The essential oil contains 33 constituents which are being identified for the first time in S. oblonga. The essential oil exhibited testosterone level enhancing property which is dose dependent in male albino rats.
Keywords: Chemical composition, Essential oil, Sterculia oblonga, Testosterone level
SUPPORTING INFORMATION
Author Contributions
Frank N I Morah - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Emmanuel A Bisong - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2019 Frank N I Morah et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
